Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 253
interventional 230
Observational 22
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 123
Drug|placebo 30
Procedure 13
Device 10
Device|Drug 10
Drug|Other 9
Other 8
Drug|Procedure 6
Device|Procedure 3
Device|Drug|Other 2
Device|Drug|Procedure 2
Device|Drug|Radiation 2
Diagnostic Test 2
Dietary Supplement 2
Behavioral|Device 1
Combination Product 1
Device|Drug|Other|placebo 1
Device|Other|Procedure 1
Dietary Supplement|placebo 1
Drug|Other|placebo 1
Drug|placebo|Procedure 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 110
Germany 19
NA 16
Bangladesh 9
Australia 6
United States|Australia 6
Brazil 5
Denmark 5
Korea, Republic of 5
Canada 4
Taiwan 4
United Kingdom 4
China 3
Finland 3
Italy 3
France 2
Norway 2
United States|Canada 2
United States|Puerto Rico 2
Australia|Canada|France|Germany|United Kingdom 1
Australia|Germany 1
Australia|New Zealand 1
Austria|Denmark|Germany|Iceland|United Kingdom 1
Austria|France|Germany 1
Austria|Germany 1
Canada|United States 1
Denmark|Germany|Norway|Sweden|United Kingdom 1
France|Germany 1
France|Germany|Netherlands|Spain|Sweden 1
France|Germany|United Kingdom 1
Germany|Greece 1
Germany|Switzerland 1
Germany|United Kingdom 1
Israel 1
Lithuania 1
Netherlands 1
Sweden 1
Switzerland 1
United States|Germany 1

Sites per Study

Site_count Study_Count
1 147
2 7
3 7
4 6
5 1
6 4
7 3
8 3
9 3
10 3
11 3
13 4
14 1
16 2
17 3
18 3
19 1
20 4
21 3
22 1
23 2
24 2
25 1
26 4
27 1
28 1
30 3
31 1
32 1
35 1
40 1
46 1
57 1
61 1

Phase

Phase Study_Count
Phase 3 61
Phase 2 55
N/A 44
Phase 4 31
Phase 1 29
Phase 1/Phase 2 7
Phase 2/Phase 3 2
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 44
2 97
3 43
4 18
5 4
7 1
8 4
10 1
NA 18

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 132 7.00000 2.0000 14.0000 12.00000 47.00 12.0000 9.0000
1st Qu. 132 21.75000 24.0000 36.0000 30.00000 95.25 129.0000 20.5000
Median 132 33.00000 45.0000 220.0000 60.00000 143.50 367.0000 47.0000
Mean 132 74.88636 90.2069 166.4286 86.58491 143.50 332.4098 132.6129
3rd Qu. 132 63.00000 79.0000 269.5000 119.00000 191.75 470.0000 235.5000
Max. 132 461.00000 443.0000 320.0000 266.00000 240.00 889.0000 579.0000

Trial Group Type

group_type Group_Count
Experimental 235
Active Comparator 149
Placebo Comparator 95
Other 19
NA 18
No Intervention 7
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 155
Single Group Assignment 58
Factorial Assignment 6
Sequential Assignment 6
Crossover Assignment 3
NA 2

Primary Purpose

primary_purpose Study_Count
Treatment 197
Prevention 9
NA 9
Other 7
Diagnostic 5
Health Services Research 2
Basic Science 1

Observational Studies

Studies by Country

Country Study_Count
United States 7
NA 4
Germany 3
United States|Australia 2
Australia|France|Italy|Netherlands|Spain|Switzerland|United Kingdom 1
Egypt 1
Greece 1
Korea, Republic of 1
Netherlands 1
Norway 1

Sites per Study

Site_count Study_Count
1 15
6 1
7 1
8 1
11 1
13 1
17 1
42 1

Enrollment Metrics

Measure Observational
Min 43.0000
1st Qu 98.0000
Median 179.0000
Mean 371.0952
3rd Qu 440.0000
Max 1324.0000

Observation Model

observational_model Study_Count
Cohort 7
Case-Only 5
NA 5
Other 2
Case-Control 1
Case Control 1
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 17
NA 2
Longitudinal, Prospective 1
Other 1
Retrospective 1

Registries

Studies by Country

Country Study_Count
United States 1

Sites per Study

Site_count Study_Count
1 1

Enrollment Metrics

Measure Registries
Min 100
1st Qu 100
Median 100
Mean 100
3rd Qu 100
Max 100

Registry Model

observational_model Study_Count
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03826550 Therapeutic Equivalence of Diclofenac Sodium Gel 3% vs Solaraze ® in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT03826550 Completed Encube Ethicals Pvt. Ltd. 2018-06-30
NCT03325803 Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03325803 Completed Dong-A University 2016-09-30
NCT03322293 Daylight Photodynamic Therapy for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03322293 Completed University of California, San Francisco 2018-12-01
NCT03315286 Validation of SHADE a Mobile Technology for Monitoring of Ultraviolet Exposure https://ClinicalTrials.gov/show/NCT03315286 Completed Weill Medical College of Cornell University 2019-01-31
NCT03285490 A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp (AK004) https://ClinicalTrials.gov/show/NCT03285490 Completed Athenex, Inc. 2019-04-30
NCT03285477 A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp https://ClinicalTrials.gov/show/NCT03285477 Completed Athenex, Inc. 2019-04-30
NCT03246412 Nevus Doctor Clinical Decision Support for GPs https://ClinicalTrials.gov/show/NCT03246412 Recruiting University Hospital of North Norway 2020-12-31
NCT03243617 Cosmetic Study of AO+Mist in Improving the Appearance of Skin Afflicted With Keratosis Pilaris https://ClinicalTrials.gov/show/NCT03243617 Completed AOBiome LLC 2016-06-08
NCT03200912 An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT03200912 Completed Actavis Inc. 2017-03-07
NCT03127670 Effect of Solanum Melongena Extract in the Treatment of Arsenical Skin Lesion https://ClinicalTrials.gov/show/NCT03127670 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2017-12-31
NCT03122457 Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide https://ClinicalTrials.gov/show/NCT03122457 Completed Icahn School of Medicine at Mount Sinai 2018-07-19
NCT03116698 A Study to Evaluate Two Concentrations of DFD-07 Cream, in Subjects With Actinic Keratosis (AK) of the Face and/or Scalp Over a 12-week Treatment Period https://ClinicalTrials.gov/show/NCT03116698 Completed Dr. Reddy’s Laboratories Limited 2017-11-13
NCT03076892 Evaluation of Non-inferiority and Tolerability of the Device PHOS-ISTOS https://ClinicalTrials.gov/show/NCT03076892 Completed University Hospital, Lille 2017-11-30
NCT03066843 Photodynamic Therapy Incubation Times for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03066843 Active, not recruiting Northwestern University 2021-12-31
NCT03037541 Cryosurgery and Cream Combination for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03037541 Completed Wake Forest University Health Sciences 2013-10-29
NCT03006185 Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin https://ClinicalTrials.gov/show/NCT03006185 Completed Bispebjerg Hospital 2016-11-30
NCT02990221 Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy https://ClinicalTrials.gov/show/NCT02990221 Completed University of Campania “Luigi Vanvitelli” 2018-04-30
NCT02976727 Efficacy of Topical Calcipotriol-assisted AFL-PDT in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02976727 Completed Dong-A University 2015-08-31
NCT02952898 Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses https://ClinicalTrials.gov/show/NCT02952898 Completed Gage Development Company, LLC 2017-07-11
NCT02938715 Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil https://ClinicalTrials.gov/show/NCT02938715 Completed University of California, Davis 2017-09-30
NCT02902822 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo https://ClinicalTrials.gov/show/NCT02902822 Completed Centro Studi Gised 2019-05-31
NCT02878382 Potential Impact of Patient Vitamin D Status in AK Response to MAL-PDT https://ClinicalTrials.gov/show/NCT02878382 Completed University of Sao Paulo 2017-01-31
NCT02866695 Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients https://ClinicalTrials.gov/show/NCT02866695 Completed University of California, San Francisco 2018-07-02
NCT02844777 Efficacy and Safety of VDA-1102 Ointment in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT02844777 Completed Vidac Pharma 2017-05-31
NCT02838628 A Phase 2a, Activity & Safety Study of KX2-391 Ointment in Subjects With Actinic Keratosis on the Face or Scalp https://ClinicalTrials.gov/show/NCT02838628 Completed Athenex, Inc. 2016-12-31
NCT02799082 Evaluation of Efficacy and Safety of BF-200 ALA Used With Photodynamic Therapy in Patients With Actinic Keratosis. https://ClinicalTrials.gov/show/NCT02799082 Completed Biofrontera Bioscience GmbH 2008-10-31
NCT02799069 Evaluation of Safety and Efficacy of BF-200 ALA for the Treatment of Actinic Keratosis With Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02799069 Completed Biofrontera Bioscience GmbH 2009-08-31
NCT02799030 A Clinical Trial of Topical Photodynamic Therapy With 5-aminolevulinic Acid for the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT02799030 Completed Biofrontera Bioscience GmbH 2007-03-31
NCT02759900 Using a Cold Atmospheric Plasma Device to Treat Skin Disorders https://ClinicalTrials.gov/show/NCT02759900 Recruiting The Skin Center Dermatology Group 2022-03-31
NCT02716714 Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02716714 Completed Korea University 2016-06-30
NCT02670655 Efficacy of Iontophoresis-assisted AFL-PDT in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02670655 Completed Dong-A University 2015-12-31
NCT02667288 An Open-Label Safety Study of A-101 Solution https://ClinicalTrials.gov/show/NCT02667288 Completed Aclaris Therapeutics, Inc. 2016-10-31
NCT02667275 A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis https://ClinicalTrials.gov/show/NCT02667275 Completed Aclaris Therapeutics, Inc. 2016-10-31
NCT02667236 A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis. https://ClinicalTrials.gov/show/NCT02667236 Completed Aclaris Therapeutics, Inc. 2016-10-31
NCT02654769 A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02654769 Completed Actavis Inc. 2015-09-30
NCT02654717 Eight Week Study of Treatment With DFD-07 for Actinic Keratosis of the Face and Scalp https://ClinicalTrials.gov/show/NCT02654717 Completed Promius Pharma, LLC 2016-08-31
NCT02650505 A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel https://ClinicalTrials.gov/show/NCT02650505 Completed LEO Pharma 2016-06-30
NCT02632110 Microneedle Lesion Preparation Prior to Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) for AK on Face https://ClinicalTrials.gov/show/NCT02632110 Completed DUSA Pharmaceuticals, Inc. 2016-09-12
NCT02628236 Maximal Use Systemic Exposure Study of Levulan Kerastick (MUSE 2) https://ClinicalTrials.gov/show/NCT02628236 Completed DUSA Pharmaceuticals, Inc. 2016-05-31
NCT02622594 Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times https://ClinicalTrials.gov/show/NCT02622594 Completed Dermatology, Laser & Vein Specialists of the Carolinas 2017-04-13
NCT02616601 Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02616601 Completed Actavis Inc. 2015-09-17
NCT02611804 A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Multicenter Study Comparing Diclofenac Sodium Gel, 3% to Solaraze® Gel, 3% in the Treatment of Actinic Keratosis on the Face or Bald Scalp https://ClinicalTrials.gov/show/NCT02611804 Completed Teva Pharmaceuticals USA 2016-08-31
NCT02600598 Biological Effects of LEO 43204 in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02600598 Completed LEO Pharma 2016-12-27
NCT02594644 The Use of Microneedles to Expedite Treatment Time in Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02594644 Completed University of California, Davis 2016-06-22
NCT02984072 Menthol for PDT Pain Relief https://ClinicalTrials.gov/show/NCT02984072 Completed University of Dundee 2019-10-10
NCT02559934 Multiple-dose Pharmacokinetic Study of Solamargine in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02559934 Completed G&E Herbal Biotechnology Co., LTD 2019-01-31
NCT02124733 Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses https://ClinicalTrials.gov/show/NCT02124733 Completed The Cleveland Clinic 2016-10-31
NCT02549352 Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up https://ClinicalTrials.gov/show/NCT02549352 Completed LEO Pharma 2016-09-22
NCT02549339 Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up https://ClinicalTrials.gov/show/NCT02549339 Completed LEO Pharma 2016-08-05
NCT03684772 Topical Ionic Contra-Viral Therapy in Actinic Keratosis https://ClinicalTrials.gov/show/NCT03684772 Recruiting Maruho Co., Ltd. 2019-09-30
NCT02547363 Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up https://ClinicalTrials.gov/show/NCT02547363 Completed LEO Pharma 2016-08-17
NCT02547233 Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up https://ClinicalTrials.gov/show/NCT02547233 Completed LEO Pharma 2016-11-30
NCT02520700 A Comparison of White-light and Daylight Topical Methyl 5-aminolaevulinic Acid Photodynamic Therapy for Actinic Keratoses https://ClinicalTrials.gov/show/NCT02520700 Completed St Vincent’s University Hospital, Ireland 2015-05-31
NCT02464709 Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL) https://ClinicalTrials.gov/show/NCT02464709 Completed Joint Authority for Päijät-Häme Social and Health Care 2017-10-31
NCT02459795 To Compare Safety and Efficacy of Perrigo’s Drug Compared to an FDA Approved Drug in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT02459795 Completed Perrigo Company 2015-12-31
NCT02451579 A Clinical Trial Evaluating the Role of Systemic Antihistamine Therapy in the Reduction of Adverse Effects Associated With Topical 5-aminolevulinic Acid Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02451579 Completed Goldman, Butterwick, Fitzpatrick and Groff 2016-12-31
NCT02446223 Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015% https://ClinicalTrials.gov/show/NCT02446223 Completed Goldman, Butterwick, Fitzpatrick and Groff 2016-09-30
NCT02424305 Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions https://ClinicalTrials.gov/show/NCT02424305 Completed LEO Pharma 2015-07-31
NCT02411851 Treatment of Actinic Keratoses (AK) on the Face https://ClinicalTrials.gov/show/NCT02411851 Completed Icahn School of Medicine at Mount Sinai 2016-06-30
NCT02404389 Safety, Tolerability, and Efficacy Study of LFX453 in Actinic Keratosis Patients https://ClinicalTrials.gov/show/NCT02404389 Completed Novartis 2016-01-27
NCT02385318 To Compare Safety and Efficacy of Perrigo’s Drug Product Compared to an FDA Approved Drug Product in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT02385318 Completed Perrigo Company 2015-12-31
NCT02373371 Actinic Keratoses Treatment With Metvix® in Combination With Light https://ClinicalTrials.gov/show/NCT02373371 Completed University Hospital, Limoges 2016-11-22
NCT02361216 Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest https://ClinicalTrials.gov/show/NCT02361216 Completed LEO Pharma 2016-03-31
NCT02354391 Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT02354391 Active, not recruiting Pacific Dermaesthetics 2019-12-31
NCT02352987 Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the Treatment of Arsenical Palmar Keratosis https://ClinicalTrials.gov/show/NCT02352987 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2015-09-30
NCT02337205 Ph 1, Single-Center, Safety, Tolerability & Pharmacokinetic Study of KX2 391 Ointment in Subj. w Actinic Keratosis https://ClinicalTrials.gov/show/NCT02337205 Completed Athenex, Inc. 2016-03-31
NCT02325661 Open Uncontrolled Validation Study for the German Version of the Actinic Keratosis Quality of Life Questionnaire (AKQoL) https://ClinicalTrials.gov/show/NCT02325661 Completed University of Zurich 2014-12-31
NCT02305888 Safety of LEO 43204 for Actinic Keratosis Applied on Face/Chest, Scalp and Trunk/Extremities, Respectively https://ClinicalTrials.gov/show/NCT02305888 Completed LEO Pharma 2015-07-31
NCT02289768 Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic Keratoses https://ClinicalTrials.gov/show/NCT02289768 Completed Almirall, S.A. 2015-09-30
NCT02281136 Maximal Use Systemic Exposure (MUSE) Study of Levulan Kerastick https://ClinicalTrials.gov/show/NCT02281136 Completed DUSA Pharmaceuticals, Inc. 2015-04-30
NCT02278861 Oral Isotretinoin Versus Topical Tretinoin for Actinic Keratosis https://ClinicalTrials.gov/show/NCT02278861 Completed Universidade Federal de Goias 2014-04-30
NCT02260180 Study of A-101 for the Treatment of Seborrheic Keratosis https://ClinicalTrials.gov/show/NCT02260180 Completed Aclaris Therapeutics, Inc. 2015-03-31
NCT02251652 Safety and Efficacy of Ingenol Mebutate 0.05% Gel When Used After Cryotherapy in the Hypertrophic Actinic Keratoses https://ClinicalTrials.gov/show/NCT02251652 Completed Icahn School of Medicine at Mount Sinai 2014-12-31
NCT02248298 Efficacy of AFL-assisted PDT With Short Incubation Time in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02248298 Completed Dong-A University 2014-06-30
NCT02242747 Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis https://ClinicalTrials.gov/show/NCT02242747 Completed University of Sao Paulo 2014-07-31
NCT02239679 Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic Therapy https://ClinicalTrials.gov/show/NCT02239679 Completed DUSA Pharmaceuticals, Inc. 2016-07-31
NCT02160626 Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis https://ClinicalTrials.gov/show/NCT02160626 Completed Aclaris Therapeutics, Inc. 2014-12-31
NCT02149342 Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL https://ClinicalTrials.gov/show/NCT02149342 Completed Joint Authority for Päijät-Häme Social and Health Care 2015-09-30
NCT02137785 Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities https://ClinicalTrials.gov/show/NCT02137785 Completed DUSA Pharmaceuticals, Inc. 2015-03-31
NCT02126670 ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02126670 Completed Promius Pharma, LLC 2014-09-30
NCT02124239 Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions https://ClinicalTrials.gov/show/NCT02124239 Completed LEO Pharma 2014-11-30
NCT02120898 A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses https://ClinicalTrials.gov/show/NCT02120898 Completed Actavis Inc. 2014-04-30
NCT02120456 Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02120456 Completed LEO Pharma 2015-05-31
NCT02085395 Clinical Study Assessment of SR-T100 Topical Gel Against Actinic Keratosis https://ClinicalTrials.gov/show/NCT02085395 Completed G&E Herbal Biotechnology Co., LTD 2010-04-30
NCT02062853 Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video https://ClinicalTrials.gov/show/NCT02062853 Completed University of California, Davis 2016-06-30
NCT01302925 PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects https://ClinicalTrials.gov/show/NCT01302925 Completed Peplin 2011-03-31
NCT01281644 Treatment of Keratosis Pilaris With 810 nm Diode Laser https://ClinicalTrials.gov/show/NCT01281644 Completed Northwestern University 2011-10-31
NCT02029066 Pharmacokinetic Study of Solamargine in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02029066 Completed G&E Herbal Biotechnology Co., LTD 2014-02-28
NCT02019355 Actinic Keratosis Study https://ClinicalTrials.gov/show/NCT02019355 Completed Washington University School of Medicine 2015-03-31
NCT01998984 Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT01998984 Completed LEO Pharma 2014-07-31
NCT01986920 Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis https://ClinicalTrials.gov/show/NCT01986920 Completed Aclaris Therapeutics, Inc. 2014-02-25
NCT01966120 Safety and Efficacy Study for the Field-directed Treatment of Actinic Keratosis (AK) With Photodynamic Therapy (PDT) https://ClinicalTrials.gov/show/NCT01966120 Completed Biofrontera Bioscience GmbH 2014-09-30
NCT01962987 A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® (Diclofenac Sodium) Gel 3% in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT01962987 Completed Actavis Inc. 2013-09-30
NCT01935531 Effects of Topical Diclofenac on Tumor Metabolism https://ClinicalTrials.gov/show/NCT01935531 Completed University Hospital Regensburg 2016-01-31
NCT01922050 A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT01922050 Completed LEO Pharma 2014-11-30
NCT01921907 Evaluation of a Topical Treatment for Actinic Keratosis https://ClinicalTrials.gov/show/NCT01921907 Completed Assuta Hospital Systems 2014-06-30
NCT01905891 Nanocytology Test to Evaluate Skin Cancer in High Risk Patients https://ClinicalTrials.gov/show/NCT01905891 Completed Northwestern University 2014-11-30
NCT01898936 Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic for Treatment of Actinic Keratoses https://ClinicalTrials.gov/show/NCT01898936 Completed Oslo University Hospital 2016-09-30
NCT04319159 Study to Evaluate the Safety of BF-200 ALA (Ameluz®) for Photodynamic Therapy (PDT) in the Treatment of Expanded Fields of Actinic Keratosis (AK) https://ClinicalTrials.gov/show/NCT04319159 Recruiting Biofrontera Bioscience GmbH 2020-09-30
NCT01892137 Histological Confirmation of Clinical Clearance of Actinic Keratoses Following Treatment With Ingenol Mebutate Gel, 0.05% https://ClinicalTrials.gov/show/NCT01892137 Completed LEO Pharma 2014-03-31
NCT01836367 Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp https://ClinicalTrials.gov/show/NCT01836367 Completed Icahn School of Medicine at Mount Sinai 2013-08-31
NCT01821391 Phase 3b Study of Metvix NDL-PDT Versus Metvix c-PDT in Subjects With Actinic Keratoses https://ClinicalTrials.gov/show/NCT01821391 Completed Galderma 2014-01-31
NCT01820260 Safety and Efficacy of Doses of Ingenol Mebutate Once Daily for Two or Three Consecutive Days in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT01820260 Completed LEO Pharma 2014-08-31
NCT01812837 The Use of Microneedles in Photodynamic Therapy https://ClinicalTrials.gov/show/NCT01812837 Completed University of California, Davis 2014-03-31
NCT01803477 Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm https://ClinicalTrials.gov/show/NCT01803477 Completed LEO Pharma 2013-10-31
NCT01787383 A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities https://ClinicalTrials.gov/show/NCT01787383 Completed LEO Pharma 2014-01-31
NCT01757613 Study Whose Purpose is to Find an Optimal Dose for the Treatment With AK 3012 in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT01757613 Completed Dolorgiet GmbH & Co. KG 2014-01-31
NCT01752972 Effect of Spirulina on Zinc, Vitamin E and Linoleic Acid Levels in Palm Skin Following Chronic Exposure to Arsenic https://ClinicalTrials.gov/show/NCT01752972 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2011-12-31
NCT01748669 Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis https://ClinicalTrials.gov/show/NCT01748669 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2012-07-31
NCT01742663 A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® Gel 3% in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT01742663 Completed Taro Pharmaceuticals USA 2013-07-31
NCT01735097 Effect of Nigella Sativa in the Treatment of Palmer Arsenical Keratosis https://ClinicalTrials.gov/show/NCT01735097 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2013-11-30
NCT01731756 Effects of Leaf Extract of Azadirachta Indica in Palmer Arsenical Keratosis https://ClinicalTrials.gov/show/NCT01731756 Completed Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2013-12-31
NCT01703078 Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT01703078 Completed LEO Pharma 2013-03-31
NCT01686152 Study Comparing Imiquimod Cream, 3.75% to Zyclara® (Imiquimod) Cream, 3.75% in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT01686152 Completed Teva Pharmaceuticals USA 2013-08-31
NCT01600014 Ingenol Mebutate Gel, 0.015% Repeat Use for Multiple Actinic Keratoses on Face and Scalp https://ClinicalTrials.gov/show/NCT01600014 Completed LEO Pharma 2014-02-28
NCT01583816 Dose-finding, Safety, Efficacy Trial of Topical Resiquimod in Patients With Multiple Actinic Keratosis Lesions https://ClinicalTrials.gov/show/NCT01583816 Completed Spirig Pharma Ltd. 2013-11-30
NCT03327831 Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses https://ClinicalTrials.gov/show/NCT03327831 Completed University of California, Irvine 2017-02-28
NCT01541553 A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp https://ClinicalTrials.gov/show/NCT01541553 Completed LEO Pharma 2013-07-31
NCT01516515 Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis https://ClinicalTrials.gov/show/NCT01516515 Completed G&E Herbal Biotechnology Co., LTD 2017-12-31
NCT01502020 A Bioequivalence Study With Clinical Endpoints Comparing Generic Imiquimod Cream, 3.75% and Zyclaraâ„¢ (Imiquimod) Cream, 3.75% in Subjects With Actinic Keratoses https://ClinicalTrials.gov/show/NCT01502020 Completed Actavis Mid-Atlantic LLC 2011-08-31
NCT01493921 Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment https://ClinicalTrials.gov/show/NCT01493921 Completed G&E Herbal Biotechnology Co., LTD 2015-11-30
NCT01475955 Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK) https://ClinicalTrials.gov/show/NCT01475955 Completed DUSA Pharmaceuticals, Inc. 2012-11-30
NCT01475071 Intra-individual Comparison of Efficacy and Safety of Metvix® Natural Daylight Photodynamic Therapy Versus Conventional Metvix® Photodynamic Therapy in Subject With Mild Actinic Keratoses https://ClinicalTrials.gov/show/NCT01475071 Completed Galderma 2012-11-30
NCT01459393 Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment https://ClinicalTrials.gov/show/NCT01459393 Completed Barretos Cancer Hospital 2011-11-30
NCT01458587 Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK) https://ClinicalTrials.gov/show/NCT01458587 Completed DUSA Pharmaceuticals, Inc. 2012-07-31
NCT01453179 Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2) https://ClinicalTrials.gov/show/NCT01453179 Completed MEDA Pharma GmbH & Co. KG 2015-03-31
NCT01449513 PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy https://ClinicalTrials.gov/show/NCT01449513 Completed LEO Pharma 2012-05-31
NCT01444989 Development and Validation of a Quality of Life Instrument for Actinic Keratosis https://ClinicalTrials.gov/show/NCT01444989 Completed Wake Forest University Health Sciences 2011-12-31
NCT01442727 Selenium in the Treatment of Arsenic Toxicity and Cancers https://ClinicalTrials.gov/show/NCT01442727 Completed Texas Tech University 2009-04-30
NCT01387711 PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology https://ClinicalTrials.gov/show/NCT01387711 Completed LEO Pharma 2012-06-30
NCT01358851 LAS41005 in Hyperkeratotic Actinic Keratosis https://ClinicalTrials.gov/show/NCT01358851 Completed Almirall, S.A. 2012-03-31
NCT01354717 Bioequivalence Study of Generic Fluorouracil 0.5% Cream and 0.5% Carac® and Placebo https://ClinicalTrials.gov/show/NCT01354717 Completed Spear Pharmaceuticals 2011-03-31
NCT04336514 A Longitudinal Quantitative Assessment of the Effectiveness of Metatarsal Pads on Plantar Pressures https://ClinicalTrials.gov/show/NCT04336514 Active, not recruiting University Health Network, Toronto 2021-05-31
NCT04269395 A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study https://ClinicalTrials.gov/show/NCT04269395 Recruiting Galderma R&D 2020-06-30
NCT04249115 Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Optimization Study https://ClinicalTrials.gov/show/NCT04249115 Active, not recruiting Pulse Biosciences, Inc. 2020-02-29
NCT04229277 Fast Track Diagnosis of Skin Cancer by Advanced Imaging https://ClinicalTrials.gov/show/NCT04229277 Active, not recruiting University Hospital Bispebjerg and Frederiksberg 2020-03-22
NCT04085367 Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face https://ClinicalTrials.gov/show/NCT04085367 Recruiting Galderma R&D 2020-10-06
NCT03963102 Duration of Ameluz Application in Acral Actinic Keratoses Response https://ClinicalTrials.gov/show/NCT03963102 Recruiting Royal Cornwall Hospitals Trust 2020-10-01
NCT03914417 Genomic Markers Before and After Treatment of Actinic Keratosis With Imiquimod 3.75% Cream https://ClinicalTrials.gov/show/NCT03914417 Completed Icahn School of Medicine at Mount Sinai 2016-06-30
NCT03906253 Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia https://ClinicalTrials.gov/show/NCT03906253 Recruiting Wright State Physicians 2025-12-31
NCT03846531 Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Study https://ClinicalTrials.gov/show/NCT03846531 Completed Pulse Biosciences, Inc. 2017-11-13
NCT03805737 Indoor Daylight Photo Dynamic Therapy for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03805737 Recruiting Dartmouth-Hitchcock Medical Center 2020-11-30
NCT03731988 Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03731988 Completed Dong-A University 2017-10-30
NCT03727074 Bioequivalence Study to Compare Sol-Gel Technologies’ 5-FU Cream With Efudex® (5-FU) Cream https://ClinicalTrials.gov/show/NCT03727074 Completed Sol-Gel Technologies, Ltd. 2019-12-19
NCT03697590 Photodynamic Therapy of Actinic Keratosis of the Face and Scalp With and Without Prior Curettage https://ClinicalTrials.gov/show/NCT03697590 Completed Bispebjerg Hospital 2017-12-20
NCT03643744 Photodynamic Therapy-Induced Immune Modulation: Part III https://ClinicalTrials.gov/show/NCT03643744 Recruiting Wright State Physicians 2021-03-31
NCT03642535 Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention https://ClinicalTrials.gov/show/NCT03642535 Recruiting Shanghai Dermatology Hospital 2025-06-01
NCT03635853 Identification of Compound Isolated From Cock’s Comb and Its Effect on Arsenical Palmar Keratosis https://ClinicalTrials.gov/show/NCT03635853 Recruiting Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2018-12-31
NCT03632733 Effects of Antimicrobials on the Altered Skin Flora in Arsenical Keratosis https://ClinicalTrials.gov/show/NCT03632733 Recruiting Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 2018-10-30
NCT03606122 5-ALA Patch-PDT of Actinic Keratosis on the Upper Extremities https://ClinicalTrials.gov/show/NCT03606122 Completed photonamic GmbH & Co. KG 2019-07-16
NCT03596619 The Study of Plum-blossom Needling Enhancing Efficacy of Aminolevulinic Acid-photodynamic Therapy for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03596619 Recruiting Shanghai Dermatology Hospital 2021-12-30
NCT03575780 Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT03575780 Completed Athenex, Inc. 2019-04-25
NCT03511326 PRO With Luxerm® in the Field Treatment of Thin and Non-hyperkeratotic Non-pigmented AK https://ClinicalTrials.gov/show/NCT03511326 Completed Galderma 2017-11-28
NCT03508856 Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin https://ClinicalTrials.gov/show/NCT03508856 Completed Skin Laser & Surgery Specialists 2016-08-09
NCT03487588 An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Seborrheic Keratoses https://ClinicalTrials.gov/show/NCT03487588 Completed Aclaris Therapeutics, Inc. 2018-11-14
NCT03483935 Microwave Therapy for Treatment of Precancerous Actinic Keratoses https://ClinicalTrials.gov/show/NCT03483935 Completed University of Dundee 2019-02-28
NCT03447925 Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients https://ClinicalTrials.gov/show/NCT03447925 Recruiting Universidade do Vale do Sapucai 2019-10-01
NCT01265602 Double-blind, Randomized, Vehicle- and Comparator-controlled, Multi-center Trial to Evaluate the Efficacy and Safety of LAS41007 in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT01265602 Completed Almirall, S.A. 2012-03-31
NCT01260987 Fractional CO2 Laser Assisted Photodynamic Therapy https://ClinicalTrials.gov/show/NCT01260987 Completed Bispebjerg Hospital 2012-08-31
NCT01214564 Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic Keratosis https://ClinicalTrials.gov/show/NCT01214564 Completed Peplin 2010-12-31
NCT01159860 Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses? https://ClinicalTrials.gov/show/NCT01159860 Completed Milton S. Hershey Medical Center 2012-05-11
NCT01053000 Photodynamic Therapy With Levulan® +/- Topical Retinoid Pre-Treatment In The Treatment Of Actinic Keratoses https://ClinicalTrials.gov/show/NCT01053000 Completed Stewart, Roger H., M.D., P.A. 2010-11-30
NCT01000636 Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT) https://ClinicalTrials.gov/show/NCT01000636 Completed Galderma 2011-10-31
NCT00991861 Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT00991861 Completed Almirall, S.A. 2010-02-28
NCT00987246 Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT00987246 Completed Almirall, S.A. 2009-06-30
NCT00948428 Bioequivalence of Generic Imiquimod Cream, 5% When Compared to Aldaraâ„¢ (Imiquimod) Cream, 5% in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT00948428 Completed Actavis Inc. 2009-03-31
NCT00942604 A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations https://ClinicalTrials.gov/show/NCT00942604 Completed Peplin 2009-10-31
NCT00926952 Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion https://ClinicalTrials.gov/show/NCT00926952 Completed Innovaderm Research Inc. 2010-12-31
NCT00917306 A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities) https://ClinicalTrials.gov/show/NCT00917306 Completed Peplin 2009-09-30
NCT00916006 A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) https://ClinicalTrials.gov/show/NCT00916006 Completed Peplin 2009-09-30
NCT00915551 A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp) https://ClinicalTrials.gov/show/NCT00915551 Completed Peplin 2009-09-30
NCT00894647 Safety and Effectiveness Study of Actinic Keratosis Treatment Following Cryosurgery https://ClinicalTrials.gov/show/NCT00894647 Completed Graceway Pharmaceuticals, LLC 2010-02-28
NCT00859105 A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled Therapeutic Equivalence Study of Three Imiquimod Cream 5% Treatments for Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT00859105 Completed Apotex Inc. 2008-11-30
NCT00852137 A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT00852137 Completed Peplin 2009-06-30
NCT00850811 A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers https://ClinicalTrials.gov/show/NCT00850811 Completed Peplin 2009-04-30
NCT00850681 A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers https://ClinicalTrials.gov/show/NCT00850681 Completed Peplin 2009-04-30
NCT00843323 Photodynamic Therapy (PDT) Effect on Large Surface Photodamaged Skin https://ClinicalTrials.gov/show/NCT00843323 Completed University of Sao Paulo 2009-03-31
NCT03083470 Study of SOR007 Ointment for Actinic Keratosis https://ClinicalTrials.gov/show/NCT03083470 Completed DFB Soria, LLC 2018-03-12
NCT00828568 Bioequivalence Study of Two Imiquimod Cream 5% https://ClinicalTrials.gov/show/NCT00828568 Completed Taro Pharmaceuticals USA 2009-03-31
NCT03279328 Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents https://ClinicalTrials.gov/show/NCT03279328 Completed University of Arizona 2018-07-31
NCT01788007 Clinical Study to Evaluate the Bioequivalence of Two Imiquimod Cream 3.75% Formulations in Patients With Actinic Keratosis. https://ClinicalTrials.gov/show/NCT01788007 Completed Taro Pharmaceuticals USA 2013-10-31
NCT01611480 Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Weekly During 2 x 2 Weeks Treatment for Actinic Keratosis on the Head https://ClinicalTrials.gov/show/NCT01611480 Completed Moberg Pharma AB 2013-01-31
NCT01926496 Risk of Squamous Cell Carcinoma on Skin Areas Treated With Ingenol Mebutate Gel, 0.015% and Imiquimod Cream, 5% https://ClinicalTrials.gov/show/NCT01926496 Completed LEO Pharma 2019-07-11
NCT01893203 Daylight-PDT for AKs: Comparing Two Photosensitizers (BF-200 ALA and MAL) https://ClinicalTrials.gov/show/NCT01893203 Completed Joint Authority for Päijät-Häme Social and Health Care 2014-12-31
NCT01541228 Photodynamic Treatment of Actinic Keratoses With Different Light Doses https://ClinicalTrials.gov/show/NCT01541228 Completed Lithuanian University of Health Sciences 2011-04-30
NCT04140292 Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses https://ClinicalTrials.gov/show/NCT04140292 Recruiting Case Comprehensive Cancer Center 2021-12-31
NCT04396184 Conventional Photodynamic Therapy vs. Painless Photodynamic Therapy for Actinic Keratosis https://ClinicalTrials.gov/show/NCT04396184 Recruiting Shanghai Dermatology Hospital 2021-04-30
NCT03148691 A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis https://ClinicalTrials.gov/show/NCT03148691 Completed Aclaris Therapeutics, Inc. 2018-02-28
NCT02644187 Pain Relief During Photodynamic Therapy for Actinic Keratoses With a New Irradiation Protocol https://ClinicalTrials.gov/show/NCT02644187 Completed Vastra Gotaland Region 2017-03-31
NCT02406014 Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp https://ClinicalTrials.gov/show/NCT02406014 Completed LEO Pharma 2016-06-30
NCT02100813 Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis https://ClinicalTrials.gov/show/NCT02100813 Completed LEO Pharma 2015-03-31
NCT03210740 Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis https://ClinicalTrials.gov/show/NCT03210740 Completed AmDerma 2018-02-13
NCT00786994 The Efficacy and Tolerability of Oleogel-S-10 in Patients With Actinic Keratoses https://ClinicalTrials.gov/show/NCT00786994 Completed Amryt Pharma 2010-11-30
NCT00777127 Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses https://ClinicalTrials.gov/show/NCT00777127 Completed MEDA Pharma GmbH & Co. KG 2012-11-30
NCT00774787 Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses https://ClinicalTrials.gov/show/NCT00774787 Completed Rigel Dermatology 2010-03-31
NCT00742391 A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations https://ClinicalTrials.gov/show/NCT00742391 Completed Peplin 2009-02-28
NCT00711178 A Randomized Multicenter Study of Daylight Mediated Photodynamic Therapy (PDT) https://ClinicalTrials.gov/show/NCT00711178 Completed Bispebjerg Hospital 2009-01-31
NCT00710203 Dermatosis Papulosa Nigra https://ClinicalTrials.gov/show/NCT00710203 Completed University of California, Davis 2009-12-31
NCT00700063 A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp) https://ClinicalTrials.gov/show/NCT00700063 Completed Peplin 2008-10-31
NCT00696488 Measuring Adherence To Topical 5-Fluorouracil in a Clinic Population https://ClinicalTrials.gov/show/NCT00696488 Completed Wake Forest University Health Sciences 2007-08-31
NCT00695578 Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy https://ClinicalTrials.gov/show/NCT00695578 Completed Wake Forest University Health Sciences 2007-06-30
NCT00659893 Safety and Toleration of PEP005 Topical Gel When Applied to a Treatment Area of up to 100cm2 https://ClinicalTrials.gov/show/NCT00659893 Completed Peplin 2008-11-30
NCT00605176 Safety and Effectiveness Study of Imiquimod Creams for Treatment of Actinic Keratoses (AKs) https://ClinicalTrials.gov/show/NCT00605176 Completed Graceway Pharmaceuticals, LLC 2008-07-31
NCT00603798 Safety and Effectiveness Study of Imiquimod Creams for the Treatment of Actinic Keratoses (AKs) https://ClinicalTrials.gov/show/NCT00603798 Completed Graceway Pharmaceuticals, LLC 2008-07-31
NCT00558688 A Photodynamic Therapy for Treatment of Actinic Keratoses https://ClinicalTrials.gov/show/NCT00558688 Completed Northwestern University 2009-08-31
NCT00544297 A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand https://ClinicalTrials.gov/show/NCT00544297 Completed Peplin 2008-01-31
NCT00544258 Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005 https://ClinicalTrials.gov/show/NCT00544258 Completed Peplin 2008-05-31
NCT00472459 PDT With Metvix® 160 mg/g Cream in Organ Transplant Recipients With Non-melanoma Skin Cancer https://ClinicalTrials.gov/show/NCT00472459 Completed Galderma NA
NCT00432224 Treatment of Actinic Keratoses With Photodynamic Therapy Using Sunlight Versus Red Light https://ClinicalTrials.gov/show/NCT00432224 Completed Bispebjerg Hospital NA
NCT00427050 A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel https://ClinicalTrials.gov/show/NCT00427050 Completed Peplin 2007-11-30
NCT00377273 An Open-Label 18-Month Safety Study of Fluorouracil Cream 0.5% for the Treatment of Actinic Keratoses https://ClinicalTrials.gov/show/NCT00377273 Completed Sanofi NA
NCT00375739 Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses https://ClinicalTrials.gov/show/NCT00375739 Completed Peplin 2007-06-30
NCT00335179 Cellular and Molecular Events During Treatment of Actinic Keratosis With Imiquimod 5% Cream https://ClinicalTrials.gov/show/NCT00335179 Completed Graceway Pharmaceuticals, LLC 2003-07-31
NCT00308867 PD P 506 A-PDT Versus Placebo-PDT and Cryosurgery for the Treatment of AK https://ClinicalTrials.gov/show/NCT00308867 Completed photonamic GmbH & Co. KG 2007-06-30
NCT00308854 Photodynamic Therapy With PD P 506 A Compared With Placebo-PDT for the Treatment of AK https://ClinicalTrials.gov/show/NCT00308854 Completed photonamic GmbH & Co. KG 2007-08-31
NCT00306800 Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp https://ClinicalTrials.gov/show/NCT00306800 Completed Galderma NA
NCT00304239 Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp https://ClinicalTrials.gov/show/NCT00304239 Completed Galderma NA
NCT00294320 Evaluation of Two Different Non-Invasive Techniques to Monitor the Clearance of Actinic Keratosis Lesions https://ClinicalTrials.gov/show/NCT00294320 Completed MEDA Pharma GmbH & Co. KG 2007-01-31
NCT00269074 Effect of IDEA-070 on Pain and Inflammation Induced by PDT https://ClinicalTrials.gov/show/NCT00269074 Completed IDEA AG NA
NCT00239135 Study to Determine the Maximum Tolerated Dose and Safety of PEP005 Topical Gel https://ClinicalTrials.gov/show/NCT00239135 Completed Peplin 2005-12-31
NCT00204542 Comparison of the Efficacy and Tolerability of Solaraze for 3 Versus 6 Months in Patients With Mild to Moderate Actinic Keratosis Located on the Face and Head https://ClinicalTrials.gov/show/NCT00204542 Completed University Hospital Tuebingen 2009-03-31
NCT00189267 A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant Recipients https://ClinicalTrials.gov/show/NCT00189267 Completed MEDA Pharma GmbH & Co. KG NA
NCT00175643 Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses https://ClinicalTrials.gov/show/NCT00175643 Completed University of British Columbia NA
NCT00121511 The Effect of Efudex Treatment on Photoaged Skin https://ClinicalTrials.gov/show/NCT00121511 Completed University of Michigan NA
NCT00116649 Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis https://ClinicalTrials.gov/show/NCT00116649 Completed Graceway Pharmaceuticals, LLC 2007-05-31
NCT00115154 Study to Assess the Safety and Efficacy of Imiquimod 5% Cream for the Treatment of Actinic Keratosis on the Arms and Hands https://ClinicalTrials.gov/show/NCT00115154 Completed Graceway Pharmaceuticals, LLC NA
NCT00110682 Study of Imiquimod 5% Cream in Addition to Cryotherapy in the Management of Actinic Keratoses https://ClinicalTrials.gov/show/NCT00110682 Completed Derm Research @ 888 Inc. 2006-10-31
NCT00107965 Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses https://ClinicalTrials.gov/show/NCT00107965 Completed Peplin 2005-09-30
NCT00089180 T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplant https://ClinicalTrials.gov/show/NCT00089180 Completed National Cancer Institute (NCI) 2007-01-31
NCT00021294 Eflornithine With or Without Triamcinolone in Preventing Nonmelanoma Skin Cancer in Patients With Actinic Keratosis https://ClinicalTrials.gov/show/NCT00021294 Completed University of Arizona 2002-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT02674048 Metvix Daylight PDT in Actinic Keratosis https://ClinicalTrials.gov/show/NCT02674048 Completed Galderma 2016-10-31
NCT02594436 The Use of Picato® (Ingenol Mebutate) to Treat Actinic Keratosis in Standard Clinical Practice https://ClinicalTrials.gov/show/NCT02594436 Completed LEO Pharma 2017-11-30
NCT02421471 PMS to Evaluate the Safety and Efficacy of Picato® Gel https://ClinicalTrials.gov/show/NCT02421471 Completed LEO Pharma 2018-01-19
NCT02362152 The Real Life Topical Field Treatment of Actinic Keratosis Study https://ClinicalTrials.gov/show/NCT02362152 Completed LEO Pharma 2015-12-31
NCT02209012 Twelve Month Follow-Up of CP0108 https://ClinicalTrials.gov/show/NCT02209012 Completed DUSA Pharmaceuticals, Inc. 2016-02-29
NCT02090465 Assessment of Treatment Success and Quality of Life in Patients With Actinic Keratoses Under Therapy With Ingenol Mebutate in a Period of 8 Weeks https://ClinicalTrials.gov/show/NCT02090465 Completed LEO Pharma 2013-12-31
NCT01571336 Photodynamic Therapy of Actinic Keratoses With Alacare® https://ClinicalTrials.gov/show/NCT01571336 Completed photonamic GmbH & Co. KG 2016-05-31
NCT04267419 Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions https://ClinicalTrials.gov/show/NCT04267419 Completed Beni-Suef University 2019-12-15
NCT04202445 TreatMent of ActInic KerAtosis Lesions : pharmacoepiDemiological Study of the Impact in Real Life of ingenOl Mebutate Gel (Picato®) on Patients Satisfaction https://ClinicalTrials.gov/show/NCT04202445 Completed LEO Pharma 2016-02-29
NCT04024579 Treatment of Actinic Keratosis With 5% KOH Solution https://ClinicalTrials.gov/show/NCT04024579 Completed Infectopharm Arzneimittel GmbH 2019-08-25
NCT01151956 Imiquimod and Actinic Keratoses: an Observational Study https://ClinicalTrials.gov/show/NCT01151956 Completed Federal University Teaching Hospital, Feldkirch, Austria NA
NCT00989313 A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study https://ClinicalTrials.gov/show/NCT00989313 Completed Peplin 2010-10-31
NCT00952783 A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study https://ClinicalTrials.gov/show/NCT00952783 Completed Peplin 2010-10-31
NCT00953732 A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies https://ClinicalTrials.gov/show/NCT00953732 Completed Peplin 2010-10-31
NCT00710489 Potential Research Study Participant Registry https://ClinicalTrials.gov/show/NCT00710489 Completed University of California, Davis 2018-09-05
NCT00668733 Follow-up Study to Evaluate Sustained Clearance Rates of Actinic Keratoses up to One Year https://ClinicalTrials.gov/show/NCT00668733 Completed Graceway Pharmaceuticals, LLC 2009-07-31
NCT00540566 Optical Biopsy of Human Skin in Conjunction With Laser Treatment https://ClinicalTrials.gov/show/NCT00540566 Completed University of California, Irvine 2008-06-30
NCT00218868 Cytodiagnosis of Basal Cell Carcinoma and Actinic Keratosis Using Papanicolaou and May-grunwald-giemsa Stained Tissue Smear https://ClinicalTrials.gov/show/NCT00218868 Completed Norwegian University of Science and Technology 2006-02-28
NCT00189254 A Study to Follow up Recurrence Rates of Actinic Keratoses One Year After Completion of Study 1487-IMIQ https://ClinicalTrials.gov/show/NCT00189254 Completed MEDA Pharma GmbH & Co. KG 2005-11-30
NCT00114023 1-Year Follow up to the 1473-IMIQ Study https://ClinicalTrials.gov/show/NCT00114023 Completed Graceway Pharmaceuticals, LLC NA
NCT00001292 Study of Scaling Disorders and Other Inherited Skin Diseases https://ClinicalTrials.gov/show/NCT00001292 Completed National Institutes of Health Clinical Center (CC) NA
NCT00005660 The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases https://ClinicalTrials.gov/show/NCT00005660 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03319251 Biomarker Database Registry for Photodynamic Therapy https://ClinicalTrials.gov/show/NCT03319251 Recruiting The Cleveland Clinic 2021-11-30